Differential regulation of prostaglandin F(2alpha) receptor isoforms by protein kinase C.

@article{Fujino2000DifferentialRO,
  title={Differential regulation of prostaglandin F(2alpha) receptor isoforms by protein kinase C.},
  author={Hiromichi Fujino and Dinesh Srinivasan and Kristen L. Pierce and John W. Regan},
  journal={Molecular pharmacology},
  year={2000},
  volume={57 2},
  pages={353-8}
}
Prostaglandin F(2alpha) receptors (FP) are G protein-coupled receptors that bind prostaglandin F(2alpha) (PGF(2alpha)), resulting in the activation of an inositol phosphate (IP) second messenger pathway. Alternative mRNA splicing generates two FP receptor isoforms. These isoforms, designated FP(A) and FP(B), are otherwise identical except for their carboxyl termini. FP(B) is essentially a truncated version of FP(A) that lacks the 46 carboxyl-terminal amino acids, including four putative protein… CONTINUE READING

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Recent progress in hormone research • 1996
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