Differential regulation of mRNAs encoding three protein-tyrosine phosphatases by insulin and activation of protein kinase C.

@article{Hashimoto1992DifferentialRO,
  title={Differential regulation of mRNAs encoding three protein-tyrosine phosphatases by insulin and activation of protein kinase C.},
  author={Naotake Hashimoto and Barry J. Goldstein},
  journal={Biochemical and biophysical research communications},
  year={1992},
  volume={188 3},
  pages={1305-11}
}
Protein-tyrosine phosphatases (PTPases) play an essential role in the control of signalling through phosphotyrosine pathways. Since little is known about the regulation of these enzymes, we examined the effect of insulin and phorbol 12-myristate 13-acetate (PMA) treatment of well-differentiated rat hepatoma (Fao) cells on the expression of mRNAs encoding… CONTINUE READING