Differential regulation of interleukin 17 and interferon γ production in inflammatory bowel disease

@article{Rovedatti2009DifferentialRO,
  title={Differential regulation of interleukin 17 and interferon $\gamma$ production in inflammatory bowel disease},
  author={Laura Rovedatti and Takahiro Kudo and Paolo Biancheri and Massimiliano Sarra and Charles H. Knowles and David S. Rampton and G. R. Corazza and Giovanni Monteleone and Antonio Di Sabatino and Thomas T. Macdonald},
  journal={Gut},
  year={2009},
  volume={58},
  pages={1629 - 1636}
}
Background and Aims: Interleukin 17 (IL17) is now known to be involved in a number of chronic inflammatory disorders. However, the mechanisms regulating its production in inflammatory bowel disease (IBD) are still unclear. Methods: Endoscopic biopsies or surgical specimens were taken from inflamed and uninflamed colonic mucosa of 72 patients with IBD (38 with Crohn’s disease and 34 with ulcerative colitis), and normal colon of 38 control subjects. IL17 and interferon γ (IFNγ) were detected by… 
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