Differential regulation of immature articular cartilage compressive moduli and Poisson's ratios by in vitro stimulation with IGF-1 and TGF-beta1.

@article{Williams2010DifferentialRO,
  title={Differential regulation of immature articular cartilage compressive moduli and Poisson's ratios by in vitro stimulation with IGF-1 and TGF-beta1.},
  author={Gregory Williams and Kristin J Dills and Christian R Flores and Michael E. Stender and Kevin Matthew Stewart and Lauren May Nelson and Albert C. Chen and Koichi Masuda and Scott J. Hazelwood and Stephen M. Klisch and Robert L. Sah},
  journal={Journal of biomechanics},
  year={2010},
  volume={43 13},
  pages={2501-7}
}
Mechanisms of articular cartilage growth and maturation have been elucidated by studying composition-function dynamics during in vivo development and in vitro culture with stimuli such as insulin-like growth factor-1 (IGF-1) and transforming growth factor-beta 1 (TGF-beta1). This study tested the hypothesis that IGF-1 and TGF-beta1 regulate immature cartilage compressive moduli and Poisson's ratios in a manner consistent with known effects on tensile properties. Bovine calf articular cartilage… CONTINUE READING

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Structural changes during development in bovine fetal epiphyseal cartilage.

Collagen and related research • 1981
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