Differential regulation of gliogenesis in the context of adult hippocampal neurogenesis in mice.

@article{Steiner2004DifferentialRO,
  title={Differential regulation of gliogenesis in the context of adult hippocampal neurogenesis in mice.},
  author={Barbara Steiner and Golo Kronenberg and Sebastian Jessberger and Moritz D. Brandt and Katja Reuter and Gerd Kempermann},
  journal={Glia},
  year={2004},
  volume={46 1},
  pages={41-52}
}
In adult hippocampal neurogenesis, new neurons appear to originate from a cell with astrocytic properties expressing glial fibrillary acidic protein (GFAP). Also, new astrocytes are generated in the adult dentate gyrus. Whereas the putative astrocyte-like progenitor cells are consistently S-100beta-negative, many new astrocytes are S-100beta-positive. Thus, it is unclear whether the GFAP-positive progenitor cells are astrocytes in a general sense or rather neural progenitor cells with certain… CONTINUE READING
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