Differential regulation of germ line apoptosis and germ cell differentiation by CPEB family members in C. elegans

@article{Singh2017DifferentialRO,
  title={Differential regulation of germ line apoptosis and germ cell differentiation by CPEB family members in C. elegans},
  author={Kapil Dev Singh and Xue Zheng and Stuart Milstein and Martin Keller and Bernd Roschitzki and Jonas Grossmann and Michael O. Hengartner},
  journal={PLoS ONE},
  year={2017},
  volume={12}
}
Cytoplasmic polyadenylation element binding (CPEB) proteins are evolutionary conserved RNA-binding proteins that control mRNA polyadenylation and translation. Orthologs in humans and other vertebrates are mainly involved in oogenesis. This is also the case for the C. elegans CPEB family member CPB-3, whereas two further CPEB proteins (CPB-1 and FOG-1) are involved in spermatogenesis. Here we describe the characterisation of a new missense allele of cpb-3 and show that loss of cpb-3 function… 
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