Differential regulation of alpha- and beta-CGRP mRNAs within oculomotor, trochlear, abducens, and trigeminal motoneurons in response to axotomy.

@article{Fukuoka1999DifferentialRO,
  title={Differential regulation of alpha- and beta-CGRP mRNAs within oculomotor, trochlear, abducens, and trigeminal motoneurons in response to axotomy.},
  author={T OSHIHIRO O DA Fukuoka and Atsushi Tokunaga and Eiji Kondo and Kensuke Miki and Toshiya Tachibana and Koichi Noguchi},
  journal={Brain research. Molecular brain research},
  year={1999},
  volume={63 2},
  pages={304-15}
}
Spinal and cranial motoneurons express alpha- and beta-calcitonin gene-related peptide (CGRP) mRNAs constitutively at variable ratios, and these two mRNAs are differentially regulated following axotomy in spinal, facial, and hypoglossal motoneurons. The purpose of this study was to investigate the change in CGRP mRNA expression following nerve injury in oculomotor, trochlear, abducens, and trigeminal motor nuclei in which beta-CGRP mRNA is predominantly expressed under normal conditions. Using… CONTINUE READING
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