Differential regulation of Tec1 by Fus3 and Kss1 confers signaling specificity in yeast development

@article{Brckner2004DifferentialRO,
  title={Differential regulation of Tec1 by Fus3 and Kss1 confers signaling specificity in yeast development},
  author={Stefan Br{\"u}ckner and Tim K{\"o}hler and Gerhard H Braus and Barbara Heise and Melanie Bolte and Hans-Ulrich Moesch},
  journal={Current Genetics},
  year={2004},
  volume={46},
  pages={331-342}
}
Transcriptional regulation by mitogen-activated protein (MAP) kinase signaling cascades is a major control mechanism for eukaryotic development. In budding yeast, Fus3 and Kss1 are two MAP kinases that control two distinct developmental programs—mating and invasive growth. We investigated whether signal-specific activation of mating and invasive growth involves regulation of the transcription factor Tec1 by Fus3 and Kss1. We present evidence that, during mating, Fus3 phosphorylates Tec1 to… CONTINUE READING

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