Differential rates of replacement of human dermal dendritic cells and macrophages during hematopoietic stem cell transplantation

@inproceedings{Haniffa2009DifferentialRO,
  title={Differential rates of replacement of human dermal dendritic cells and macrophages during hematopoietic stem cell transplantation},
  author={Muzlifah Haniffa and Florent Ginhoux and Xiao-nong Wang and Venetia Bigley and Michal Abel and Ian Dimmick and Sarah L Bullock and Marcos G Grisotto and Trevor Booth and Peter James Taub and Catharien M. U. Hilkens and Miriam Merad and Matthew Collin},
  booktitle={The Journal of experimental medicine},
  year={2009}
}
Animal models of hematopoietic stem cell transplantation have been used to analyze the turnover of bone marrow-derived cells and to demonstrate the critical role of recipient antigen-presenting cells (APC) in graft versus host disease (GVHD). In humans, the phenotype and lineage relationships of myeloid-derived tissue APC remain incompletely understood. It has also been proposed that the risk of acute GVHD, which extends over many months, is related to the protracted survival of certain… CONTINUE READING