Differential proteome of bone marrow mesenchymal stem cells from osteoarthritis patients.

  title={Differential proteome of bone marrow mesenchymal stem cells from osteoarthritis patients.},
  author={Raquel Roll{\'i}n and Fiore Marco and Emilio Camafeita and Emilio Calvo and Luis E L{\'o}pez-Duran and Juan {\'A}ngel Jover and Jose Alejandro Poveda Lopez and Benjam{\'i}n Fern{\'a}ndez-Guti{\'e}rrez},
  journal={Osteoarthritis and cartilage},
  volume={16 8},
OBJECTIVE Adult mesenchymal stem cells (MSCs) are multipotent cells whose primary reservoir is bone marrow (BM). Following situations of extensive tissue damage, MSCs are mobilized and migrate to the site of injury. Osteoarthritis (OA) is a condition that involves extensive cartilage and bone damage. To gain insight into the pathogenesis of OA, we have analyzed the differential BM-MSCs proteome of OA patients. METHODS MSCs protein extracts were prepared from BM aspirates from six patients… CONTINUE READING


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