Differential proteolysis of sigma regulators controls cell‐surface signalling in Pseudomonas aeruginosa

@article{Draper2011DifferentialPO,
  title={Differential proteolysis of sigma regulators controls cell‐surface signalling in Pseudomonas aeruginosa},
  author={Richard Charles Draper and Lois W. Martin and Paul A. Beare and Iain L. Lamont},
  journal={Molecular Microbiology},
  year={2011},
  volume={82}
}
Cell‐surface signalling systems are widespread in Gram‐negative bacteria. In these systems gene expression occurs following binding of a ligand, commonly a siderophore, to a receptor protein in the outer membrane. The receptor interacts with a sigma regulator protein that extends from the periplasm into the cytoplasm to control the activity of a cognate sigma factor. The mechanisms of signal transduction in cell‐surface signalling systems have not been determined. Here we investigate signal… Expand
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