Differential protein expression in Tree Shrew sclera during development of lens-induced myopia and recovery

@inproceedings{Frost2007DifferentialPE,
  title={Differential protein expression in Tree Shrew sclera during development of lens-induced myopia and recovery},
  author={Michael R. Frost and Thomas B. Norton},
  booktitle={Molecular vision},
  year={2007}
}
PURPOSE The tree shrew model of refractive development is particularly useful because, like humans, tree shrews have a fibrous sclera. Selective changes in some candidate extracellular matrix proteins and mRNAs have been found in the sclera during the development of and recovery from induced myopia. We undertook a more neutral proteomic analysis using two-dimensional gel electrophoresis and mass spectrometry to identify scleral proteins that are differentially expressed during the development… CONTINUE READING
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Differential expression of collagen types I, III and V in the sclera of myopic eyes: A precursor to fibril diameter changes

  • A Gentle, JE Martin, NA. McBrien
  • Invest Ophthalmol Vis Sci
  • 2002
Highly Influential
8 Excerpts

Regulation of the mechanical properties of tree shrew sclera by the visual environment

  • Siegwart JT, TT Norton
  • Vision Res
  • 1999
Highly Influential
5 Excerpts

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