Differential promoter usage of mouse mu-opioid receptor gene during development.

@article{Ko2002DifferentialPU,
  title={Differential promoter usage of mouse mu-opioid receptor gene during development.},
  author={Jane L. Ko and Hung-Chen Chen and Horace H. Loh},
  journal={Brain research. Molecular brain research},
  year={2002},
  volume={104 2},
  pages={184-93}
}
Previously, we demonstrated that mouse mu-opioid receptor (MOR) gene expression is regulated by both distal and proximal promoters, with the latter playing a major role in controlling MOR transcription in the adult mouse brain. Here, we report studies of the relative usages of the mouse MOR dual promoters during murine development. We used the reverse transcription-polymerase chain reaction (RT-PCR) method, which gave results similar to those using binding assays or in situ hybridization… CONTINUE READING