Differential promoter activity by nucleotide substitution at a type 2 diabetes genome-wide association study signal upstream of the wolframin gene.

Abstract

BACKGROUND Functional knowledge of most genetic variants identified from genome-wide association studies (GWAS) for type 2 diabetes (T2D) is limited. A recent T2D GWAS revealed an association signal (rs4689388) upstream of the gene encoding Wolfram syndrome 1 (WFS1) whose intrinsic nucleotide variants had been previously associated with T2D in several… (More)
DOI: 10.1111/1753-0407.12289

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Cite this paper

@article{Ryu2016DifferentialPA, title={Differential promoter activity by nucleotide substitution at a type 2 diabetes genome-wide association study signal upstream of the wolframin gene.}, author={Jihye Ryu and Chaeyoung Lee}, journal={Journal of diabetes}, year={2016}, volume={8 2}, pages={253-9} }