Differential processing of neurotensin/neuromedin N precursor(s) in canine brain and intestine.

@article{Carraway1990DifferentialPO,
  title={Differential processing of neurotensin/neuromedin N precursor(s) in canine brain and intestine.},
  author={R. Carraway and S. P. Mitra},
  journal={The Journal of biological chemistry},
  year={1990},
  volume={265 15},
  pages={
          8627-31
        }
}
  • R. Carraway, S. P. Mitra
  • Published 1990
  • Medicine, Biology
  • The Journal of biological chemistry
  • By using a radioimmunoassay for neuromedin N (NMN), a hexapeptide in the neurotensin (NT) family, extracts of canine small intestine were found to contain primarily (greater than 75%) large molecular form(s) of NMN, whereas the predominant species in brain was NMN itself. Large NMN was highly basic (pI greater than 9) and during sodium dodecyl sulfate gel electrophoresis gave two components of approximately 17 kDa (75%) and approximately 8 kDa (25%). Large NMN, like NT, was localized primarily… CONTINUE READING
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