Differential phosphorylation of connexin46 and connexin50 by H2O2 activation of protein kinase Cgamma.

@article{Lin2004DifferentialPO,
  title={Differential phosphorylation of connexin46 and connexin50 by H2O2 activation of protein kinase Cgamma.},
  author={Dingbo Lin and Samuel S Lobell and Andrea D Jewell and Dolores J. Takemoto},
  journal={Molecular vision},
  year={2004},
  volume={10},
  pages={688-95}
}
PURPOSE Fiber cell gap junction proteins connexin 46 (Cx46) and connexin 50 (Cx50) play distinct roles in the avascular lens. The purpose of this study was to determine how protein kinase Cgamma (PKCgamma) differentially regulates phosphorylation of Cx46 and Cx50 in oxidatively stressed lenses. METHODS Sprague Dawley rats (six week old) were used in the… CONTINUE READING