Differential patterns of regional c-Fos induction in the rat brain by amphetamine and the novel wakefulness-promoting agent modafinil

@article{Engber1998DifferentialPO,
  title={Differential patterns of regional c-Fos induction in the rat brain by amphetamine and the novel wakefulness-promoting agent modafinil},
  author={Thomas M. Engber and Elizabeth J. Koury and Shelley A Dennis and Matthew S. Miller and Ratan V. Bhat},
  journal={Neuroscience Letters},
  year={1998},
  volume={241},
  pages={95-98}
}
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112 Citations
Highly Influential Citations
9
Background Citations
44
Methods Citations
4
Results Citations
4

112 Citations

The brain pattern of c-fos induction by two doses of amphetamine suggests different brain processing pathways and minor contribution of behavioural traits

Differential effects of stress and amphetamine administration on Fos‐like protein expression in corticotropin releasing factor‐neurons of the rat brain

The present results indicate that stress and amphetamine elicited a distinct pattern of brain Fos‐like protein expression and differentially activated some of the brain CRF neuronal populations, despite similar levels of overall FLI in the case of IMO and Amphetamine.

Environmental Novelty Differentially Affects c-fosmRNA Expression Induced by Amphetamine or Cocaine in Subregions of the Bed Nucleus of the Stria Terminalis and Amygdala

The data suggest that the context in which psychostimulants are given powerfully and differentially alters the response of limbic structures that have been functionally implicated in drug reinforcement and emotional behaviors.

Distinct pattern of c-fos mRNA expression after systemic and intra-accumbens amphetamine and MK-801

The central nucleus of the amygdala and the wake-promoting effects of modafinil

Hypothalamic Arousal Regions Are Activated during Modafinil-Induced Wakefulness

Modafinil may promote waking via activation of TMN and orexin neurons, two regions implicated in the promotion of normal wakefulness, and Selective pharmacological activation of these hypothalamic regions may represent a novel approach to inducing wakefulness.

Effect of the wake-promoting agent modafinil on sleep-promoting neurons from the ventrolateral preoptic nucleus: an in vitro pharmacologic study.

Results suggest that modafinil blocks the reuptake of Noradrenaline by the noradrenergic terminals on sleep-promoting neurons from the VLPO, suggesting that such a mechanism could be at least partially responsible for the wake-promoted effect of modafInil.

Amphetamine-Induced Fos is Reduced in Limbic Cortical Regions but not in the Caudate or Accumbens in a Genetic Model of NMDA Receptor Hypofunction

A neuroanatomically selective activation deficit to amphetamine challenge in the NR1-deficient mice is suggested, which may have relevance to the hypothesized NMDA receptor hypofunction in schizophrenia.

Immediate-early gene expression in the central nucleus of the amygdala is not specific for anxiolytic or anxiogenic drugs

Effects of differential rearing on amphetamine-induced c-fos expression in rats.

...

References

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