Differential outcome of concurrent radiotherapy plus epidermal growth factor receptor inhibitors versus radiotherapy plus cisplatin in patients with human papillomavirus-related head and neck cancer

@inproceedings{Pajares2012DifferentialOO,
  title={Differential outcome of concurrent radiotherapy plus epidermal growth factor receptor inhibitors versus radiotherapy plus cisplatin in patients with human papillomavirus-related head and neck cancer},
  author={Bella Isabel Pajares and Jos{\'e} Manuel Trigo and Maria Dolores Toledo and Martina {\'A}lvarez and Carlos Gonz{\'a}lez-Hermoso and Antonio Rueda and Jos{\'e} Antonio Valero Medina and Vanessa de Luque and Jos{\'e} Manuel Jerez and Emilio Alba},
  booktitle={BMC Cancer},
  year={2012}
}
Human papillomavirus (HPV)-related head and neck cancer has been associated with an improved prognosis in patients treated with radiotherapy (RT) +/− chemotherapy (CT); however, RT combined with epidermal growth factor receptor (EGFR) inhibitors has not been fully studied in this group of patients. Immunohistochemical expression of p16 and PCR of HPV16 DNA were retrospectively analyzed in tumor blocks from 108 stage III/IV head and neck cancer patients treated with RT+CT (56) or RT+EGFR… CONTINUE READING
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