Differential neuronal loss following early postnatal alcohol exposure.

  title={Differential neuronal loss following early postnatal alcohol exposure.},
  author={David R. Pierce and Charles R. Goodlett and James R. West},
  volume={40 2},
Neonatal rats were exposed to 6.6 g/kg of alcohol each day between postnatal days 4 and 10 while artificial-rearing procedures were used, in a manner which produced high peak and low trough blood alcohol concentrations each day. Gastrostomy controls were reared artificially with maltose/dextrin isocalorically substituted for alcohol in the milk formula, and suckle controls were reared normally by dams. The pups were sacrificed on day 10 and tissue sections (2 microns thick) were obtained in the… CONTINUE READING


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