Differential network biology

@inproceedings{Ideker2012DifferentialNB,
  title={Differential network biology},
  author={Trey Ideker and Nevan J. Krogan},
  booktitle={Molecular systems biology},
  year={2012}
}
Protein and genetic interaction maps can reveal the overall physical and functional landscape of a biological system. To date, these interaction maps have typically been generated under a single condition, even though biological systems undergo differential change that is dependent on environment, tissue type, disease state, development or speciation. Several recent interaction mapping studies have demonstrated the power of differential analysis for elucidating fundamental biological responses… CONTINUE READING

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