Differential modulatory effects of morphine on acute and chronic stress induced neurobehavioral and cellular markers in rats.

Abstract

The present study evaluated the effects of morphine treatments on elevated plus maze test parameters, oxidative stress markers and Hsp70 expression in normal and stressed rats. Acute and chronic stress caused neurobehavioral suppression, altered prooxidant-antioxidant balance and increased Hsp70 expression in brain homogenates in a differential manner… (More)
DOI: 10.1016/j.ejphar.2014.01.058

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