Differential modulation of short and long latency sensory responses in the SI cortex by IL-6.

@article{Shin1997DifferentialMO,
  title={Differential modulation of short and long latency sensory responses in the SI cortex by IL-6.},
  author={Hyoseon Shin and Soo Jin Oh and Sung Cherl Jung and Jong Seong Park and Chung-ho Won},
  journal={Neuroreport},
  year={1997},
  volume={8 13},
  pages={2841-4}
}
The effects of topical application of interleukin-6 (IL-6) on the short and long latency evoked unit responses of the neurones in the primary somatosensory (SI) cortex were determined quantitatively in anaesthetized rats. IL-6 (0.01, 0.1, 1.0 units) significantly suppressed (-15.13 +/- 3.4%) short latency afferent sensory responses, while it induced profound facilitation (+464.74 +/- 132.7%) of long latency responses in a dose-dependent manner. IL-6-induced afferent modulations fully recovered… CONTINUE READING