Differential modulation of inflammatory pain by a selective estrogen receptor beta agonist.

Abstract

To understand the contribution of the estrogen receptor beta, the potent and selective agonist ERb-131 was evaluated in animal models of inflammatory pain. In paradigms of acute and persistent inflammatory pain, ERb-131 did not alleviate the nociception induced by either carrageenan or formalin. However, in the chronic complete Freund's adjuvant model, ERb… (More)
DOI: 10.1016/j.ejphar.2008.06.107

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