Differential modulation of adenylyl cyclases I and II by various G beta subunits.

Abstract

The accepted dogma concerning the regulation of adenylyl cyclase (AC) activity by G beta gamma dimers states that the various isoforms of AC respond differently to the presence of free G beta gamma. It has been demonstrated that AC I activity is inhibited and AC II activity is stimulated by G beta gamma subunits. This result does not address the possible… (More)

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@article{Bayewitch1998DifferentialMO, title={Differential modulation of adenylyl cyclases I and II by various G beta subunits.}, author={Michael Bayewitch and Tomer Avidor-Reiss and R. Levy and Thomas Pfeuffer and Iftach Nevo and William F. Simonds and Zvi Vogel}, journal={The Journal of biological chemistry}, year={1998}, volume={273 4}, pages={2273-6} }