Differential microarray analysis of Drosophila mushroom body transcripts using chemical ablation.

@article{Kobayashi2006DifferentialMA,
  title={Differential microarray analysis of Drosophila mushroom body transcripts using chemical ablation.},
  author={Masatomo Kobayashi and Lydia Michaut and Ayako Ino and Ken Honjo and Taiki Nakajima and Yasushi Maruyama and Hiroaki Mochizuki and Mai Ando and Indrayani Ghangrekar and Kuniaki Takahashi and Kaoru Saigo and Ryu Ueda and W. J. Gehring and Katsuo Furukubo-Tokunaga},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={2006},
  volume={103 39},
  pages={
          14417-22
        }
}
Mushroom bodies (MBs) are the centers for olfactory associative learning and elementary cognitive functions in the Drosophila brain. As a way to systematically elucidate genes preferentially expressed in MBs, we have analyzed genome-wide alterations in transcript profiles associated with MB ablation by hydroxyurea. We selected 100 genes based on microarray data and examined their expression patterns in the brain by in situ hybridization. Seventy genes were found to be expressed in the… CONTINUE READING

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