Differential microRNA signature of human mesenchymal stem cells from different sources reveals an "environmental-niche memory" for bone marrow stem cells.

@article{Ragni2013DifferentialMS,
  title={Differential microRNA signature of human mesenchymal stem cells from different sources reveals an "environmental-niche memory" for bone marrow stem cells.},
  author={Enrico Ragni and Tiziana Montemurro and Elisa Montelatici and Cristiana Lavazza and Mariele Vigan{\`o} and Paolo Rebulla and Rosaria Giordano and Lorenza Lazzari},
  journal={Experimental cell research},
  year={2013},
  volume={319 10},
  pages={1562-74}
}
Human mesenchymal stem cells (MSCs) are multipotent cells offering valuable hopes for the treatment of degenerative diseases. MSCs can be found among differentiated cells in many tissues and organs but, unfortunately, their phenotypic similarity hinders a robust cell characterization and discrimination from diverse tissue harvests. MicroRNAs (miRNAs) are crucial managers of gene expression with intriguing and still poorly known roles in stem cell maintenance and differentiation. To identify… CONTINUE READING
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