Differential microRNA expression in blood in multiple sclerosis.

@article{Sndergaard2013DifferentialME,
  title={Differential microRNA expression in blood in multiple sclerosis.},
  author={Helle Bach S{\o}ndergaard and Dan Hesse and Martin Krakauer and Per Soelberg S{\o}rensen and Finn Sellebjerg},
  journal={Multiple sclerosis},
  year={2013},
  volume={19 14},
  pages={
          1849-57
        }
}
BACKGROUND microRNAs (miRNAs) regulate the expression of the genome at the post-transcriptional level. They play a role in autoimmunity and inflammation, and show potential for use as therapeutic targets in many diseases. With the recent detection of miRNAs in body fluids, the possibility for using miRNAs as diagnostic biomarkers has emerged. OBJECTIVE We assessed whether miRNAs contribute to the altered immune activation state in relapsing-remitting multiple sclerosis (RRMS) patients and… CONTINUE READING

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