Differential microRNA expression in aristolochic acid-induced upper urothelial tract cancers ex vivo

@inproceedings{Tao2015DifferentialME,
  title={Differential microRNA expression in aristolochic acid-induced upper urothelial tract cancers ex vivo},
  author={Le Quang Tao and Yigang Zeng and Jun Wang and Zhihong Liu and Bing Shen and Jifu Ge and Yong Liu and YiFeng Guo and Jianxin Qiu},
  booktitle={Molecular medicine reports},
  year={2015}
}
Aristolochic acid (AA) is a carcinogenic, mutagenic and nephrotoxic compound commonly isolated from members of the plant family of Aristolochiaceae (such as Aristolochia and Asarum) and used in Chinese herbal medicine. Use of AA and AA‑containing plants causes chronic kidney disease (CKD) and upper urinary tract carcinoma (UUC); however, the underlying mechanism remains to be defined. miRNAs regulate a number of biological processes, including cell proliferation, differentiation and metabolism… CONTINUE READING

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