Differential methylation hybridization: profiling DNA methylation with a high-density CpG island microarray.


Differential methylation hybridization (DMH) is a high-throughput DNA methylation screening tool that utilizes methylation-sensitive restriction enzymes to profile methylated fragments by hybridizing them to a CpG island microarray. This array contains probes spanning all the 27,800 islands annotated in the UCSC Genome Browser. Herein we describe a revised… (More)
DOI: 10.1007/978-1-59745-522-0_8