Differential mRNA stability of the cspA gene in the cold-shock response of Escherichia coli.

@article{Goldenberg1996DifferentialMS,
  title={Differential mRNA stability of the cspA gene in the cold-shock response of Escherichia coli.},
  author={Daniel Goldenberg and Idit Azar and Amos B. Oppenheim},
  journal={Molecular microbiology},
  year={1996},
  volume={19 2},
  pages={241-8}
}
Exposure of bacterial cells to temperature changes induces the synthesis of a set proteins. We investigated the control of expression of the cspA gene, coding for the major cold-shock protein of Escherichia coli. This protein was shown to be transiently induced upon shift to low temperature. We demonstrated that the cspA mRNA is extremely unstable at 37 degrees C with a half-life of approx. 10 s. Upon shift to 15 degrees C cspA mRNA becomes highly stable. This mRNA stability is transient and is… CONTINUE READING

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