Differential leukotriene constrictor responses in human atherosclerotic coronary arteries.

@article{Allen1998DifferentialLC,
  title={Differential leukotriene constrictor responses in human atherosclerotic coronary arteries.},
  author={Sean P. Allen and Michael Dashwood and Karen Morrison and Magdi Yacoub},
  journal={Circulation},
  year={1998},
  volume={97 24},
  pages={2406-13}
}
BACKGROUND Leukotrienes are a class of biologically active lipids that have potent effects on the heart. To assess their role in coronary artery disease, we compared the contractile responses of leukotriene C4 (LTC4) and leukotriene D4 (LTD4) and their binding activity in both atherosclerotic and nonatherosclerotic human coronary arteries. We also studied… CONTINUE READING