Differential interactions of cerebellin precursor protein (Cbln) subtypes and neurexin variants for synapse formation of cortical neurons.

@article{Joo2011DifferentialIO,
  title={Differential interactions of cerebellin precursor protein (Cbln) subtypes and neurexin variants for synapse formation of cortical neurons.},
  author={Jae-Yeol Joo and S. T. Lee and Takeshi Uemura and Tomoyuki Yoshida and Misato Yasumura and Masahiko Watanabe and Masayoshi Mishina},
  journal={Biochemical and biophysical research communications},
  year={2011},
  volume={406 4},
  pages={627-32}
}
Trans-synaptic interaction of postsynaptic glutamate receptor δ2 and presynaptic neurexins (NRXNs) through cerebellin precursor protein (Cbln) 1 mediates synapse formation in the cerebellum [T. Uemura, S.J. Lee, M. Yasumura, T. Takeuchi, T. Yoshida, M. Ra, R. Taguchi, K. Sakimura, M. Mishina, Cell 141 (2010) 1068-1079]. This finding raises a question whether other Cbln family members interact with NRXNs to regulate synapse formation in the forebrain. Here, we showed that Cbln1 and Cbln2 induced… CONTINUE READING

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