Differential induction of prostaglandin E2-dependent and -independent immune suppressor cells by tumor-derived GM-CSF and M-CSF.

@article{Oghiso1993DifferentialIO,
  title={Differential induction of prostaglandin E2-dependent and -independent immune suppressor cells by tumor-derived GM-CSF and M-CSF.},
  author={Yoichi Oghiso and Yoshiko Yamada and Kiyoshi Ando and Hiroto Ishihara and Yoshisada Shibata},
  journal={Journal of leukocyte biology},
  year={1993},
  volume={53 1},
  pages={86-92}
}
Both prostaglandin E2 (PGE2)-dependent (indomethacin-sensitive) and PGE2-independent (indomethacin-insensitive) suppressor cell activities that inhibited mitogenic T cell blastogenesis appeared in the bone marrow and spleen of mice on days 20 to 30 following transplantation of NFSA fibrosarcoma molecularly expressing mRNA for both macrophage (M) and granulocyte-macrophage (GM) colony-stimulating factors (CSFs). The present study was done to characterize the two different suppressor cells… CONTINUE READING
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Splenic macrophages from tumor-bearing mmcc co-expressing Mac-l and Mac-2 antigens exert immunoregulatory functions via two distinct mechanisms

  • G. A. Watson, Fu, Y.-X, D. M. Lopez
  • j Leukoc. BioL
  • 1991
3 Excerpts

The role of tumor-derived cytokines on the immune system of mice bearing a mammary adenocarcinoma

  • Fu, -X Y., Watson, GA, M. Kasahara, D. M. Lopez
  • j Immunol
  • 1991
1 Excerpt

The role of lipocortin I in macrophagemediated immunosuppression in tumor-bearing mice

  • T. Sakata, S. Iwagami, +5 authors R. Suzuki
  • 1990
1 Excerpt

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