Differential induction of apoptosis on human lymphoblastic leukemia Nalm-6 and Molt-4 cells by various antitumor drugs.

To investigate how chemotherapy agents interact with the leukemic cell death pathway, we examined apoptosis of human lymphoblastic leukemia cells (Nalm-6 and Molt-4) treated with various anticancer drugs (etoposide (VP-16), camptothecin (CPT), adriamycin (ADR), cytosine arabinoside (Ara-C), methotrexate (MTX), 6 mercaptopurine (6MP), cyclophosphamide (CPM… CONTINUE READING