Differential in vivo potential of endothelial progenitor cells from human umbilical cord blood and adult peripheral blood to form functional long-lasting vessels.

@article{Au2008DifferentialIV,
  title={Differential in vivo potential of endothelial progenitor cells from human umbilical cord blood and adult peripheral blood to form functional long-lasting vessels.},
  author={Patrick Au and Laurence M Daheron and Dan G Duda and Kenneth S. Cohen and James Alexander Tyrrell and Ryan M Lanning and Dai Fukumura and David T Scadden and Rakesh K. Jain},
  journal={Blood},
  year={2008},
  volume={111 3},
  pages={1302-5}
}
Tissue engineering requires formation of a de novo stable vascular network. Because of their ability to proliferate, differentiate into endothelial cells, and form new vessels, blood-derived endothelial progenitor cells (EPCs) are attractive source of cells for use in engineering blood vessels. However, the durability and function of EPC-derived vessels implanted in vivo are unclear. To this end, we directly compared formation and functions of tissue-engineered blood vessels generated by… CONTINUE READING
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