Differential immune responses to acute lower respiratory illness in early life and subsequent development of persistent wheezing and asthma.

@article{Martinez1998DifferentialIR,
  title={Differential immune responses to acute lower respiratory illness in early life and subsequent development of persistent wheezing and asthma.},
  author={Fernando D. Martinez and D. A. Stern and Anne L. Wright and Lynn M. Taussig and Marilyn J. Halonen},
  journal={The Journal of allergy and clinical immunology},
  year={1998},
  volume={102 6 Pt 1},
  pages={915-20}
}
BACKGROUND Recent epidemiologic evidence suggests that 2 wheezing syndromes coexist in early life: transient wheezing, limited to early childhood, and persistent wheezing, which starts in early childhood and persists beyond that age. OBJECTIVE Whether the nature of the immune response occurring during acute lower respiratory illnesses (LRIs) in infancy differs between these 2 groups of wheezers has yet to be determined. METHODS We compared total serum IgE levels and peripheral blood… CONTINUE READING