Differential host susceptibility and bacterial virulence factors driving Klebsiella liver abscess in an ethnically diverse population

@article{Lee2016DifferentialHS,
  title={Differential host susceptibility and bacterial virulence factors driving Klebsiella liver abscess in an ethnically diverse population},
  author={I. Russel Lee and James Steven Molton and Kelly L. Wyres and Claire L. Gorrie and Jocelyn Wong and Chu Han Hoh and Jeanette Woon Pei Teo and Shirin Kalimuddin and David Chien Boon Lye and Sophia Archuleta and Kathryn E. Holt and Yunn‐Hwen Gan},
  journal={Scientific Reports},
  year={2016},
  volume={6}
}
Hypervirulent Klebsiella pneumoniae is an emerging cause of community-acquired pyogenic liver abscess. First described in Asia, it is now increasingly recognized in Western countries, commonly afflicting those with Asian descent. This raises the question of genetic predisposition versus geospecific strain acquisition. We leveraged on the Antibiotics for Klebsiella Liver Abscess Syndrome Study (A-KLASS) clinical trial ongoing in ethnically diverse Singapore, to prospectively examine the profiles… 
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