Differential gene expression profiling of vocal fold polyps and Reinke's edema by complementary DNA microarray.

@article{Duflo2006DifferentialGE,
  title={Differential gene expression profiling of vocal fold polyps and Reinke's edema by complementary DNA microarray.},
  author={Suzy M Duflo and Susan L Thibeault and Wenhua Li and Marshall E. Smith and Goetz Schade and Markus M Hess},
  journal={The Annals of otology, rhinology, and laryngology},
  year={2006},
  volume={115 9},
  pages={703-14}
}
OBJECTIVES Our purpose was to determine whether complementary DNA (cDNA) microarray analysis (MA) can establish distinct gene expression profiles for 2 phenotypically similar vocal fold lesions: Reinke's edema (RE) and polyps. Established transcript profiles can provide insight into the molecular and cellular processes involved in these diseases. METHODS Eleven RE specimens and 17 polyps were analyzed with MA for 8,745 genes. Further MA profiling was attempted within each lesion group to… CONTINUE READING

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