Differential gene expression of periodontal ligament cells after loading of static compressive force.

@article{Lee2007DifferentialGE,
  title={Differential gene expression of periodontal ligament cells after loading of static compressive force.},
  author={Yeon-hee Lee and Dong-Seok Nahm and Youn-Kwan Jung and Je-Yong Choi and Sahng Gyoon Kim and Michael Cho and Myung-hee Suwon Kim and Chang-Hoon Chae and Seong Gon Kim},
  journal={Journal of periodontology},
  year={2007},
  volume={78 3},
  pages={
          446-52
        }
}
BACKGROUND Compressive force is an important mechanical stimulus on the periodontal ligament (PDL) and is closely related to therapeutic tooth movement. In this study, early or late response genes related to the compressive stress in PDL cells were evaluated. Particularly, the expression of interleukin (IL)-6, IL-8, and alkaline phosphatase (ALP) was studied. METHODS The primary cultured cells from PDL were grown in a three-dimensional collagen gel, and received a continuous static… CONTINUE READING
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