Differential gene expression of hepatocellular carcinoma using cDNA microarray analysis.

@article{Lau2000DifferentialGE,
  title={Differential gene expression of hepatocellular carcinoma using cDNA microarray analysis.},
  author={Wan-yee Lau and Paul B-S Lai and M F Leung and Billy C.S. Leung and Nathalie Wong and Guoan Chen and T W Leung and C. T. Liew},
  journal={Oncology research},
  year={2000},
  volume={12 2},
  pages={
          59-69
        }
}
A cDNA microarray technique, which allows simultaneous analysis of differential expression of mRNA of over 4000 known human genes, was utilized to study the gene expression in 10 pairs of HCC and nontumorous tissues from ethnic Chinese patients in Hong Kong. A total of 211 genes were found to be highly expressed and 147 genes were downregulated in more than 1 out of 10 of the HCC pairs. The results were significant by two-tailed Wilcoxon test (P < or = 0.05 with 95% confidence) on the intensity… CONTINUE READING

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