Differential gene expression of adenosine A1, A2a, A2b, and A3 receptors in the human enteric nervous system.

@article{Christofi2001DifferentialGE,
  title={Differential gene expression of adenosine A1, A2a, A2b, and A3 receptors in the human enteric nervous system.},
  author={Fievos L Christofi and Helen Zhang and Jun Ge Yu and Jorge E Guzman and Jianjing Xue and Min-Ju Kim and Yan Zi Wang and Helen J. Cooke},
  journal={The Journal of comparative neurology},
  year={2001},
  volume={439 1},
  pages={46-64}
}
Adenosine receptors (ADORs) in the enteric nervous system may be of importance in the control of motor and secretomotor functions. Gene expression and distribution of neural adenosine A1, A2a, A2b, or A3 receptors (Rs) in the human intestine was investigated using immunochemical, Western blotting, RT-PCR, and short-circuit current (I(sc)) studies. Adenosine A1R, A2aR, A2bR, or A3R mRNAs were differentially expressed in neural and nonneural layers of the jejunum, ileum, colon, and cecum and in… CONTINUE READING

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