Differential gene expression in the pathogenic dermatophyte Arthroderma benhamiae in vitro versus during infection.

@article{Staib2010DifferentialGE,
  title={Differential gene expression in the pathogenic dermatophyte Arthroderma benhamiae in vitro versus during infection.},
  author={Peter Staib and Christophe Zaugg and Bernard R Mignon and Johann Weber and Maria Grumbt and Sylvain Pradervand and Keith Harshman and Monod Michel},
  journal={Microbiology},
  year={2010},
  volume={156 Pt 3},
  pages={884-95}
}
Although dermatophytes are the most common agents of superficial mycoses in humans and animals, the molecular basis of the pathogenicity of these fungi is largely unknown. In vitro digestion of keratin by dermatophytes is associated with the secretion of multiple proteases, which are assumed to be responsible for their particular specialization to colonize and degrade keratinized host structures during infection. To investigate the role of individual secreted proteases in dermatophytosis, a… CONTINUE READING
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