Differential gene expression in patients with amyotrophic lateral sclerosis.

  title={Differential gene expression in patients with amyotrophic lateral sclerosis.},
  author={Alexander Shtilbans and Soon-gang Choi and Mary E. Fowkes and Greg Khitrov and Mona Shahbazi and Jess Ting and Weijia Zhang and Yezhou Sun and Stuart C. Sealfon and Dale J. Lange},
  journal={Amyotrophic lateral sclerosis : official publication of the World Federation of Neurology Research Group on Motor Neuron Diseases},
  volume={12 4},
Our objective was to analyze gene expression pattern in muscles from patients with amyotrophic lateral sclerosis (ALS) and multifocal motor neuropathy (MMN) compared to controls. Biopsied skeletal muscles from three ALS, three MMN and three control subjects had total RNA extracted and subjected to genome-wide gene expression analysis using Affymetrix… CONTINUE READING