Differential gene expression in apoptotic 32Dcl3 cells: induction of metallothionein

Abstract

Growth factor deprivation induced cell death of the hematopoietic cell line 32Dcl3 is widely used as a model system to study apoptotic signalling pathways. Here we show that the onset of cell death after IL-3 withdrawal can be strongly delayed by either cycloheximide or actinomycin D, indicating that de novo protein synthesis is required. Subtractive cDNA… (More)
DOI: 10.1023/A:1026483508306

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