Differential gene expression between flat adenoma and normal mucosa in the colon in a microarray analysis

  title={Differential gene expression between flat adenoma and normal mucosa in the colon in a microarray analysis},
  author={Hiroto Kita and Yuichi Hikichi and Kouki Hikami and Koichi Tsuneyama and Zheng-Guo Cui and Hiroyuki Osawa and Hirohide Ohnishi and Hiroyuki Mutoh and Hiroko Hoshino and Christopher L Bowlus and Hironori Yamamoto and Kentaro Sugano},
  journal={Journal of Gastroenterology},
Flat adenomas in the colon are associated with a relatively higher potential for malignancy. Distinct genes may be involved in the development of flat adenoma. The aim of this study was to profile gene expression changes in flat adenomas in the colon. A genomewide expression analysis was carried out by using flat adenoma and adjacent normal mucosa in the colon to detect differences in gene expression. Because the right and left colon have different embryonic origins, each sample was classified… CONTINUE READING


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