Differential fungicidal activities of amphotericin B and voriconazole against Aspergillus species determined by microbroth methodology.

@article{Meletiadis2007DifferentialFA,
  title={Differential fungicidal activities of amphotericin B and voriconazole against Aspergillus species determined by microbroth methodology.},
  author={Joseph Meletiadis and Charalampos Antachopoulos and Theodouli Stergiopoulou and Spyros Pournaras and Emmanuel Roilides and Thomas J Walsh},
  journal={Antimicrobial agents and chemotherapy},
  year={2007},
  volume={51 9},
  pages={3329-37}
}
Antifungal agents may differ in their fungicidal activities against Aspergillus spp. In order to compare the fungicidal activities of voriconazole and amphotericin B against 40 isolates of Aspergillus fumigatus, A. flavus, and A. terreus, we developed a new microbroth colorimetric method for assessing fungicidal activities and determining minimal fungicidal concentrations (MFCs). This methodology follows the antifungal susceptibility testing reference method M-38A for MIC determination. After… CONTINUE READING