Differential function of RNCAM isoforms in precise target selection of olfactory sensory neurons.

@article{Alenius2003DifferentialFO,
  title={Differential function of RNCAM isoforms in precise target selection of olfactory sensory neurons.},
  author={Mattias Alenius and Staffan Bohm},
  journal={Development},
  year={2003},
  volume={130 5},
  pages={917-27}
}
Olfactory sensory neurons (OSNs) are individually specified to express one odorant receptor (OR) gene among approximately 1000 different and project with precision to topographically defined convergence sites, the glomeruli, in the olfactory bulb. Although ORs partially determine the location of convergence sites, the mechanism ensuring that axons with different OR identities do not co-converge is unknown. RNCAM (OCAM, NCAM2) is assumed to regulate a broad zonal segregation of projections by… CONTINUE READING
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