Differential filamentation of Candida albicans and Candida dubliniensis Is governed by nutrient regulation of UME6 expression.

@article{OConnor2010DifferentialFO,
  title={Differential filamentation of Candida albicans and Candida dubliniensis Is governed by nutrient regulation of UME6 expression.},
  author={Leanne O'Connor and Nicole C Caplice and David C Coleman and Derek J Sullivan and Gary P Moran},
  journal={Eukaryotic cell},
  year={2010},
  volume={9 9},
  pages={1383-97}
}
Candida dubliniensis is closely related to Candida albicans; however, it is responsible for fewer infections in humans and is less virulent in animal models of infection. C. dubliniensis forms fewer hyphae in vivo, and this may contribute to its reduced virulence. In this study we show that, unlike C. albicans, C. dubliniensis fails to form hyphae in yeast extract-peptone-dextrose (YPD) medium supplemented with 10% (vol/vol) fetal calf serum (YPDS medium). However, C. dubliniensis filaments in… CONTINUE READING
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