Differential expressions of mRNA for proteoglycans, collagens and transforming growth factor-beta in the human cervix during pregnancy and involution.

@article{WestergrenThorsson1998DifferentialEO,
  title={Differential expressions of mRNA for proteoglycans, collagens and transforming growth factor-beta in the human cervix during pregnancy and involution.},
  author={Gunilla Westergren-Thorsson and Mark Norman and Sven Bj{\"o}rnsson and U Endr{\'e}sen and Ylva Stjernholm and Gunvor Ekman and Anders Malmstr{\"o}m},
  journal={Biochimica et biophysica acta},
  year={1998},
  volume={1406 2},
  pages={203-13}
}
During pregnancy and involution, an extensive remodelling of the human cervical connective tissue occurs. This cervical ripening is one of the most pronounced physiological remodelling processes known in human connective tissue. To investigate how the remodelling is accomplished, the levels of mRNA for collagen I and III, versican and three small proteoglycans, biglycan, decorin and fibromodulin, were evaluated using Northern blots at different stages of cervical ripening. In the corresponding… CONTINUE READING