Differential expression patterns of mRNAs for P2X receptor subunits in neurochemically characterized dorsal root ganglion neurons in the rat.

@article{Kobayashi2005DifferentialEP,
  title={Differential expression patterns of mRNAs for P2X receptor subunits in neurochemically characterized dorsal root ganglion neurons in the rat.},
  author={Kimiko Kobayashi and T OSHIHIRO O DA Fukuoka and Hiroki Yamanaka and Yi Dai and Koichi Obata and Atsushi Tokunaga and Koichi Noguchi},
  journal={The Journal of comparative neurology},
  year={2005},
  volume={481 4},
  pages={377-90}
}
The ionotropic purine receptors, P2X receptors, are composed of an assembly of multiple P2X subunits. At present, seven subunits have been cloned and named "P2X1-7." We examined the precise distribution of mRNAs for these subunits in the rat lumbar dorsal root ganglion (DRG) by in situ hybridization histochemistry (ISHH) using riboprobes and characterized their expression among some neuronal subpopulations by ISHH and immunohistochemistry. P2X1 was not expressed by DRG neurons. P2X2 mRNA was… CONTINUE READING